MEPHACOR 5MG 20 F.C.TAB

ABOUT BISOPROLOL BETA1-SELECTIVE ADRENERGIC BLOCKER ANTIHYPERTENSIVE. MECHANISM OF ACTION OF BISOPROLOL BISOPROLOL IS A CARDIO SELECTIVE BETA-1 ADRENERGIC ANTAGONIST.IT HAS NEGATIVE CHRONOTROPIC AND NEGATIVE INOTROPIC EFFECTS ON HEART. IT DECREASES OXYGEN CONSUMPTION; CARDIAC WORK AND AORTIC PRESSURE. IT DECREASES CENTRAL SYMPATHETIC OUT FLOW AND ALSO DECREASES NOR ADRENALINE AND RENIN RELEASES. THE DRUG DECREASES BP IN HYPERTENSIVE INDIVIDUALS. INDICATIONS FOR BISOPROLOL 1.HYPERTENSION 2.CORONARY ARTERY DISEASES CONTRA-INDICATIONS OF BISOPROLOL 1.HYPERSENSITIVITY TO THE DRUG 2.SECOND OR THIRD DEGREE HEART BLOCK 3.CONGESTIVE HEART FAILURE 4.CARDIOGENIC SHOCK 5.SINUS BRADYCARDIA 6.CHRONIC OBSTRUCTIVE PULMONARY DISEASES 7.BRONCHIAL ASTHMA 9.PERIPHERAL ARTERIOLAR DISORDERS 10.RENAL IMPAIRMENT.