METHERGIN 0.125MG 30 SUGAR COATED TAB

METHERGINE�(METHYLERGONOVINE MALEATE) IS A SEMI-SYNTHETIC ERGOT ALKALOID USED FOR THE PREVENTION AND CONTROL OF POSTPARTUM HEMORRHAGE. METHERGINE (METHYLERGONOVINE MALEATE) ACTS DIRECTLY ON THE SMOOTH MUSCLE OF THE UTERUS AND INCREASES THE TONE RATE AND AMPLITUDE OF RHYTHMIC CONTRACTIONS. THUS IT INDUCES A RAPID AND SUSTAINED TETANIC UTEROTONIC EFFECT WHICH SHORTENS THE THIRD STAGE OF LABOR AND REDUCES BLOOD LOSS. THE ONSET OF ACTION AFTER I.V. ADMINISTRATION IS IMMEDIATE; AFTER I.M. ADMINISTRATION 2-5 MINUTES AND AFTER ORAL ADMINISTRATION 5-10 MINUTES. INDICATIONS AND USAGE FOR METHERGINE FOLLOWING DELIVERY OF PLACENTA FOR ROUTINE MANAGEMENT OF UTERINE ATONY HEMORRHAGE AND SUBINVOLUTION OF THE UTERUS. FOR CONTROL OF UTERINE HEMORRHAGE IN THE SECOND STAGE OF LABOR FOLLOWING DELIVERY OF THE ANTERIOR SHOULDER.