NABUXAN 500MG 20 COATED TAB

About Nabumetone NSAID arylalkanoic acid derivative Analgesic anti-inflammatory. Mechanism of Action of Nabumetone The parent compound is a prodrug which undergoes hepatic biotransformation to the active component 6-methoxy-2-naphthylacetic acid (6MNA) that is a potent inhibitor of prostaglandin synthesis most likely through binding to the COX-1 and COX-2 receptors.Its action is more potent on COX2. This results its antipyretic analgesics and anti-inflammatory action. Indications for Nabumetone 1. Rheumatoid arthritis 2. Osteoarthritis 3. Inflammatory conditions 4. Soft tissue injuries 5. Migraine 6. Gout