NEUROBUS 5MG 10 TAB

ABOUT BUSPIRONE PSYCHOTROPIC DRUG SEROTONIN 5-HT1A RECEPTOR PARTIAL AGONIST WEAK DOPAMINE (D2) ANTAGONIST AZASPIRODECANEDIONES DERIVATIVE SEDATIVE ANXIOLYTIC AGENT. MECHANISM OF ACTION OF BUSPIRONE BUSPIRONE HAS A PARTIAL AGONISTIC ACTION ON 5HT1A RECEPTOR AND IT STIMULATES PRESYNAPTIC AUTORECEPTORS. THIS WILL PRODUCE A DECREASE IN SEROTONIN NEURONAL ACTIVITY. IT ALSO HAS ANTAGONISTIC ACTION ON POST SYNAPTIC 5HT1A RECEPTOR. BUSPIRONE HAS A WEAK DOPAMINE (D2) ANTAGONISTIC ACTION. MOOD ELEVATION MAY BE DUE TO FACILITATION OF NORADRENERGIC SYSTEM. INDICATIONS FOR BUSPIRONE ANXIETY TYPICAL DOSAGE FOR BUSPIRONE ADULT: 15 - 30 MG / DAY IN 3 DIVIDED DOSE INITIAL DOSE: 15 MG / DAY IN 3 DIVIDED DOSE. DOSE CAN BE GRADUALLY INCREASED IN EVERY 3 DAYS. MAXIMUM DAILY DOSE: 60 MG / DAY