ORAP FORTE 4MG 20 TAB

ABOUT PIMOZIDE DIPHENYLBUTYLPIPERIDINE DERIVATIVE ANTIPSYCHOTIC ANTIDYSKINETIC. MECHANISM OF ACTION OF PIMOZIDE PIMOZIDE EXERTS ITS ANTIPSYCHOTIC ACTION BY SELECTIVELY INHIBITING THE DOPAMINE RECEPTOR. IT ALSO POSSESSES WEAK ANTIADRENERGIC ANTIHISTAMINIC ANTISEROTONIN AND ANTICHOLINERGIC ACTIONS. IT ALSO INHIBITS THE REUPTAKE OF DOPAMINE FROM THE SYNAPTIC CLEFT INDICATIONS FOR PIMOZIDE 1. CHRONIC PSYCHOSES 2. GILLES DE LA TOURETTE SYNDROME INTERACTIONS FOR PIMOZIDE ANTICONVULSANTS: PIMOZIDE MAY LOWER THE CONVULSIVE THRESHOLD. PHENOTHIAZINES TCAS OR ANTIARRHYTHMIC AGENTS: PIMOZIDE PROLONGS THE QT INTERVAL THEREFORE AVOID CONCOMITANT USE. ALCOHOL AND OTHER CNS DEPRESSANTS (HYPNOTICS SEDATIVES ANALGESICS ANXIOLYTICS ETC.): PIMOZIDE POTENTIATES THE EFFECTS OF THESE DRUGS.