PARKIMEDINE 50 MG 10 F.C. TABS

Mechanism of Action The precise mechanism by which safinamide exerts its effect in PD is unknown Inhibition of MAO-B activity by blocking the catabolism of dopamine is thought to result in an increase in dopamine levels and a subsequent increase in dopaminergic activity in the brain. Parkinson Disease Indicated as add-on treatment for patients with Parkinson disease who are currently taking levodopa/carbidopa and experiencing �off� episodes.