PEVISONE CREAM 15 GM

SIDE EFFECTS OF ECONAZOLE + TRIAMCINOLONE ACETONIDE 1.BURNING 2.ITCHING PREGNANCY RELATED INFORMATION MAY BE USED BREAST FEEDING RELATED INFORMATION USE WITH CAUTION INDICATIONS FOR ECONAZOLE + TRIAMCINOLONE ACETONIDE SKIN INFECTIONS ABOUT ECONAZOLE SYNTHETIC IMIDAZOLE DERIVATIVE ANTIFUNGAL. MECHANISM OF ACTION OF ECONAZOLE ECONAZOLE EXERTS ITS EFFECTS BY ALTERING CELLULAR MEMBRANE AND INTERFERING WITH CELLULAR ENZYMES.IT IS ACTIVE AGAINST MANY FUNGI DERMATOPHYTES AND YEASTS AS WELL AS SOME GRAM POSITIVE BACTERIA. ABOUT TRIAMCINOLONE ACETONIDE A SYNTHETIC GLUCOCORTICOID TOPICAL ANTI-INFLAMMATORY(STEROIDAL). MECHANISM OF ACTION OF TRIAMCINOLONE ACETONIDE THE DRUG EXERTS IT`S PHARMACOLOGICAL ACTION BY PENETRATING AND BINDING TO CYTOPLASMIC RECEPTOR PROTEIN AND CAUSES A STRUCTURAL CHANGE IN STEROID RECEPTOR COMPLEX. THIS STRUCTURAL CHANGE ALLOWS IT`S MIGRATION IN TO THE NUCLEUS AND THEN BINDING TO SPECIFIC SITES ON THE DNA WHICH LEADS TO TRANSCRIPTION OF SPECIFIC M-RN