RABICID 10MG 14 ENTERIC COATED TAB
سعر RABICID 10MG 14 ENTERIC COATED TAB
264.00 جنية
الشركة المنتجة لـ RABICID 10MG 14 ENTERIC COATED TAB
SIGMA
المادة الفعالة RABICID 10MG 14 ENTERIC COATED TAB
RABEPRAZOLE SODIUM
معلومات عن RABICID 10MG 14 ENTERIC COATED TAB
About Rabeprazole
Benzimidazole derivative Proton Pump Inhibitor Antiulcer.
Mechanism of Action of Rabeprazole
Rabeprazole sodium is a proton pump inhibitor. It is a prodrug. After administration it diffuses in to the parietal cell of the stomach and accumulates in the secretory canaliculi. In the acidic medium Rabeprazole is converted to sulfenamide. This sulfenamide covalently interacts with sulfhydryl (SH) group in the proton pump (H+ K+ATPase) and inhibits the exchange of extracellular K+ for intracellular H+ ion. Rabeprazole sodium irreversibly inhibits proton pumps activity and decreases gastric acid secretion. Rabeprazole produces fastest acid suppression and helps in mucin synthesis.