RHEUMATIZEN TOPICAL CREAM 60 GM

MECHANISM OF ACTION OF CAMPHOR CAMPHOR ACTS AS A RUBEFACIENT WHEN IT IS RUBBED ON THE SKIN AND CAUSES LOCALIZED VASODILATATION; WHICH GIVES FEELINGS OF COMFORT AND WARMTH. WHEN APPLIED GENTLY ON THE SKIN IT ACTS AS AN ANTI-PRURITIC AGENT AND CREATES A FEELING OF COOLNESS AND A MILD LOCAL ANAESTHETIC EFFECT AND RELIEVES ITCHING. WHEN INGESTED IN SMALL AMOUNTS IT CREATES FEELINGS OF WARMTH AND COMFORT IN THE EPIGASTRIUM. CAMPHOR ACTS AS A LOCAL ANESTHETIC ON THE RESPIRATORY PASSAGEWAYS AND CAUSING COUGH SUPPRESSION. PHARMACOKINETS OF CAMPHOR ABSORPTION: WELL ABSORBED THROUGH THE SKIN DISTRIBUTION: WIDELY DISTRIBUTED IN THE BODY AND CROSSES THE PLACENTA METABOLISM: METABOLIZED IN LIVER EXCRETION: EXCRETED MAINLY THROUGH URINE AND A MINOR PORTION IS EXCRETED THROUGH LUNGS.