ROCALTROL 0.5 MCG 30 CAPS

Mechanism of Action of Calcitriol Calcitriol is a 1 25-dihydroxycholecalciferol or a Vitamin D analogue. It increases the absorption of Calcium from intestine by forming a calcium binding protein. It reverses the signs of rickets and osteomalacia. Pharmacokinets of Calcitriol Absorption: It is readily absorbed after oral administration. Distribution: It is widely distributed in protein bound form. Metabolism: It undergoes metabolism in the liver and kidney. Excretion: It is excreted mainly in the faeces. Indications for Calcitriol 1.Management of Hypocalcaemia 2.Management of hypoparathyroidism and pseudohypoparathyroidism