T.B.ZIDE 100MG 50 TAB

About IsoniazidSHydrazine derivative Antitubercular Agent.SSMechanism of Action of IsoniazidSIsoniazid is a bactericidal drug. I t inhibits the mycolic acid synthesis which is essential for the cell wall formation. It also inhibits DNA RNA and protein synthesis and cell metabolism. As the results of these bacterial death occurs.SSIndications for IsoniazidS1.Tuberculosis (pulmonary &extra pulmonary)SInteractions for IsoniazidSAlcohol: Regular ingestion of alcohol is associated with higher incidence of INH-related hepatitis. SAluminium Salts: Oral absorption of INH reduced leading to decreased serum levels. SOral anticoagulants: Efficacy of oral anticoagulants increased. SBenzodiazepines: Activity of benzodiazepines that undergo oxidative metabolism is possibly increased. SCarbamazepine: Isoniazid hepatotoxicity & carbamazepine toxicity may occur from concurrent use. SCycloserine: Increased cycloserine related CNS side effects especially dizziness. S