TANAKAN 40MG 20 F.C.TABS

Mechanism of Action of Ginkgo Biloba The mechanism of action of ginkgo is believed to be produced by its functions as a neuroprotective agent an antioxidant a free-radical scavenger a membrane stabilizer and an inhibitor of platelet-activating factor via the terpene ginkgolide B.Other pharmacologic effects include the following: endothelium relaxation mediated by inhibition of 3 5 -cyclic GMP (guanosine monophosphate) phosphodiesterase; inhibition of age-related loss of muscarinergic cholinoceptors and ?-adrenoceptors; and stimulation of choline uptake in the hippocampus.Ginkgo extract also has been shown to inhibit beta-amyloid deposition. Indications for Ginkgo Biloba 1.Dementia 2.Cerebrovascular and peripheral activator