TENOCAM 20MG 5 SUPP

Mechanism of Action of Tenoxicam The anti-inflammatory effects of Tenoxicam may result from the inhibition of the enzyme cyclooxygenase and the subsequent peripheral inhibition of prostaglandin synthesis (prostaglandins sensitize pain receptors their inhibition accounts for the peripheral analgesic effects of tenoxicam). Antipyresis may occur due to its central action on the hypothalamus (resulting in peripheral dilation increased cutaneous blood flow and subsequent heat loss).Drug inhibits platelet aggregation (prolongs bleeding time) .It act as a scavenger for active oxygen at the site of inflammation. It also inhibits human metalloproteinases (stromelysin and collagenase) which induce cartilage breakdown.