AZACTAM 1 GM VIAL I.V./I.M. (CANCELLED)

MECHANISM OF ACTION MONOBACTAM; INHIBITS CELL WALL SYNTHESIS BY BINDING TO PENICILLIN BINDING PROTEINS. A MONOCYCLIC BETA-LACTAM ANTIBIOTIC ORIGINALLY ISOLATED FROM CHROMOBACTERIUM VIOLACEUM. IT IS RESISTANT TO BETA-LACTAMASES AND IS USED IN GRAM-NEGATIVE INFECTIONS ESPECIALLY OF THE MENINGES BLADDER AND KIDNEYS. IT MAY CAUSE A SUPERINFECTION WITH GRAM-POSITIVE ORGANISMS. INDICATION FOR THE TREATMENT OF THE FOLLOWING INFECTIONS CAUSED BY SUSCEPTIBLE GRAM-NEGATIVE MICROORGANISMS: URINARY TRACT INFECTIONS LOWER RESPIRATORY TRACT INFECTIONS SEPTICEMIA SKIN AND SKIN-STRUCTURE INFECTIONS INTRA-ABDOMINAL INFECTIONS AND GYNECOLOGIC INFECTIONS.