TOPOPRAZAN 20 MG 30 F.C.TABS

About Vonoprazan: First-in-class potassium-competitive acid blocker Mechanism of Action of Vonoprazan: A novel mechanism of action called potassium-competitive acid blockers (P-CABs) which competitively inhibits the binding of potassium ions to H+ K+-ATPase (also known as the proton pump) in the final step of gastric acid secretion in gastric parietal cells. Vonoprazan fumarate has fast-acting strong and sustained acid secretion inhibitory effects. Indications: - Gastric ulcer duodenal ulcer reflux esophagitis prevention of recurrence of gastric or duodenal ulcer during low-dose aspirin administration prevention of recurrence of gastric or duodenal ulcer during non-steroidal anti-inflammatory drug (NSAID) administration - Adjunct to Helicobacter pylori eradication in the following settings: Gastric ulcer duodenal ulcer gastric mucosa-associated lymphatic tissue (MALT) lymphoma idiopathic thrombocytopenic purpura the stomach after endoscopic resection of early stage gastric cancer or Helicobacter pylori gastritis