ZINACEF 750MG I.V/I.M VIAL (CANCELLED)

ABOUT CEFUROXIME SECOND GENERATION CEPHALOSPORIN ANTIBIOTIC. MECHANISM OF ACTION OF CEFUROXIME CEFUROXIME IS A 2ND GENERATION CEPHALOSPORIN WHICH EXERTS ITS BACTERICIDAL ACTION AGAINST BOTH GRAM POSITIVE & GRAM NEGATIVE ORGANISMS BY INHIBITING BACTERIAL CELL WALL SYNTHESIS. CEFUROXIME INHIBITS TRANSPEPTIDASE & THUS PREVENTS CROSS LINKING OF BACTERIAL CELL WALL. TRANSPEPTIDASE & ASSOCIATED PROTEINS CONSTITUTE VARIOUS TYPES OF SPECIFIC BINDING PROTEINS WHICH HAVE AFFINITY FOR CEPHALOSPORINS LIKE CEFUROXIME INDICATIONS FOR CEFUROXIME 1.MENINGITIS CAUSED BY H.INFLUENZAE MENINGOCOCCI PNEUMOCOCCI ETC. 2.GONORRHEA 3.PNEUMONIA & PULMONARY INFECTIONS 4.INFECTIONS CAUSED BY AMPICILLIN RESISTANT H. INFLUENZAE 5.SEPTICEMIA 6.TONSILLITIS 7.PHARYNGITIS 8.URINARY TRACT INFECTIONS 9.OTITIS MEDIA