ZITHROMAX 500 MG VIAL I.V. INF

DESCRIPTION: AZITHROMYCIN IS A SEMI-SYNTHETIC MACROLIDE ANTIBIOTIC OF THE AZALIDE CLASS. DOSE: ADULT: PO- RESPIRATORY TRACT SKIN AND SOFT TISSUE INFECTIONS- 500 MG ONCE DAILY FOR 3 DAYS. OR 500MG ON DAY 1 FOLLOWED BY 250MG ON DAYS 2 TO 5. TYPHOID- 500 MG ONCE DAILY FOR 7 DAYS. UNCOMPLICATED GONORRHOEA- 2 G SINGLE DOSE. GRANULOMA INGUINALE- INITIAL: 1 G THEN 500 MG/DAY UNTIL ALL LESIONS HAS HEALED COMPLETELY. CHANCROID/CHLAMYDIAL URETHRITIS: 1 G SINGLE DOSE PROPHYLAXIS OF DISSEMINATED MAC INFECTIONS 1.2 G ONCE WEEKLY. TREATMENT OR SECONDARY PROPHYLAXIS: ADMINISTERED ALONG WITH OTHER ANTIMYCOBACTERIALS: 500 MG ONCE DAILY. MECHANISM OF ACTION AZITHROMYCIN BINDS TO THE 50S SUBUNIT OF THE 70S BACTERIAL RIBOSOMES AND THEREFORE INHIBITS RNA-DEPENDENT PROTEIN SYNTHESIS IN BACTERIAL CELLS. HALF LIFE : 68 HOURS