BRICANYL 30MG/100ML SYRUP 120ML(CANCELLED)

ABOUT TERBUTALINE A ALFA2-ADRENERGIC AGONIST A FAST-ACTING BRONCHODILATOR TOCOLYTIC ANTI ASTHMA. MECHANISM OF ACTION OF TERBUTALINE TERBUTALINE IS A ?2 RECEPTOR AGONIST. TERBUTALINE DIRECTLY RELAXES THE AIRWAY SMOOTH MUSCLES AND PRODUCES BRONCHODILATION. STIMULATION OF ?2 RECEPTORS ACTIVATES GS ADENYLYL-CYCLASE -CYCLIC AMP PATH WAY AND PRODUCES REDUCTION IN SMOOTH MUSCLE TONE. ?2 RECEPTOR AGONISTS ALSO INCREASES THE CONDUCTANCE OF LARGE CA2+SENSITIVE K+ CHANNELS IN AIRWAY SMOOTH MUSCLES AND LEADS TO MEMBRANE HYPERPOLARISATION AND RELAXATION OF SMOOTH MUSCLES. TOCOLYTIC ACTION: IN PREMATURE LABOUR TERBUTALINE RELAXES UTERINE SMOOTH MUSCLES AND INHIBITS UTERINE CONTRACTIONS.