BYETTA 10MCG SOL. FOR INJ. PREFILLED PEN

ABOUT EXENATIDE ANTIDIABETIC AGENT NEW CLASS AGENT MECHANISM OF ACTION OF EXENATIDE EXENATIDE IS AN INCRETIN MIMIC THAT ACTS AS AN AGONIST AT GLUCAGON-LIKE PEPTIDE 1 (GLP-1) RECEPTOR. IT INCREASES GLUCOSE-DEPENDENT INSULIN SECRETION BY THE PANCREATIC BETA-CELLS SUPPRESSES INAPPROPRIATELY ELEVATED GLUCAGON SECRETION INCREASES BETA-CELL GROWTH/REPLICATION SLOWS GASTRIC EMPTYING AND DECREASES FOOD INTAKE. INDICATIONS FOR EXENATIDE ADJUNCT TO TYPE 2 DM INTERACTIONS FOR EXENATIDE PARACETAMOL: REDUCES THE PEAK PLASM LEVEL OF PARACETAMOL ORAL HYPOGLYCAEMIC(SULPHONYLUREAS): LEAD TO INCREASE RISK OF HYPOGLYCAEMIA WARFARIN: MAY ENHANCE ANTICOAGULANT EFFECT