CALMETANIL 1.5MG 30 F.C. TAB

About Bromazepam Benzodiazepine derivative Anxiolytic Sedative Hypnotic Skeletal muscle relaxant Mechanism of Action of Bromazepam Bromazepam binds to the GABA receptor GABAA. These will facilitates GABA mediated chloride channel opening and produce hyperpolarisation.This will produce an increase in the concentration of inhibitory neurotransmitter GABA and chloride ions and decreases firing rate of neurons.These alter normal excitatory functions of the body. Indications for Bromazepam 1.Anxiety 2.Preanaesthetic medication 3.Epigastric pain 4.Hypertension 5.Insomnia Interactions for Bromazepam Alcohol and other CNS depressants>>Enhanced CNS effect Cemetidine Disulfiram Fluoxetine Isoniazid Ketoconazole Propranalol Propoxyphene Valproic Acid: Bromazepam activity enhanced Digoxin Imipiramine&Desipramine:Enhanced activity of these drugs Levodopa:Decrease in antiparkinsonism efficacy