CEFABRUM 200MG 8 TAB

ABOUT CEFIXIME THIRD GENERATION CEPHALOSPORIN ORAL ANTIBIOTIC MECHANISM OF ACTION OF CEFIXIME CEFIXIME IS AN ORALLY ACTIVE 3RD GENERATION CEPHALOSPORIN WHICH EXERTS ITS BACTERICIDAL ACTION AGAINST BOTH GRAM POSITIVE & GRAM NEGATIVE ORGANISMS BY INHIBITING BACTERIAL CELL WALL SYNTHESIS. CEFIXIME INHIBITS TRANSPEPTIDASE & THUS PREVENTS CROSS LINKING OF BACTERIAL CELL WALL. TRANSPEPTIDASE & ASSOCIATED PROTEINS CONSTITUTE VARIOUS TYPES OF SPECIFIC BINDING PROTEINS WHICH HAVE AFFINITY FOR CEPHALOSPORINS LIKE CEFIXIME. IT IS HIGHLY ACTIVE AGAINST ENTEROBACTERIACEAE HAEMOPHILUS INFLUENZAE STREPTOCOCCUS PYOGENS & STREPTOCOCCUS PNEUMONIA &MANY BETA LACTAMASE PRODUCING BACTERIA. INDICATIONS FOR CEFIXIME 1.TONSILLITIS 2.PHARYNGITIS 3.OTITISMEDIA 4.BRONCHITIS 5.URINARY TRACT INFECTIONS 6.GONORRHEA 7.INFECTIONS CAUSED BY SUSCEPTIBLE ORGANISMS.