CEFOPERAZONE 1 GM I.M./I.V. VIAL

ABOUT CEFOPERAZONE SODIUM A THIRD GENERATION CEPHALOSPORIN ANTIBIOTIC PARENTERAL ANTIBIOTIC. MECHANISM OF ACTION OF CEFOPERAZONE SODIUM CEFOPERAZONE IS A 3RD GENERATION CEPHALOSPORIN WHICH EXERTS ITS BACTERICIDAL ACTION AGAINST BOTH GRAM POSITIVE & GRAM NEGATIVE ORGANISMS BY INHIBITING BACTERIAL CELL WALL SYNTHESIS. CEFOPERAZONE INHIBITS TRANSPEPTIDASE & THUS PREVENTS CROSS LINKING OF BACTERIAL CELL WALL. TRANSPEPTIDASE & ASSOCIATED PROTEINS CONSTITUTE VARIOUS TYPES OF SPECIFIC BINDING PROTEINS WHICH HAVE AFFINITY FOR CEPHALOSPORINS LIKE CEFOPERAZONE. IT HAS GREATER ACTION AGAINST PSEUDOMONAS & HAS GOOD ACTION AGAINST SALMONELLA TYPHI & B.FRAGILIS INDICATIONS FOR CEFOPERAZONE SODIUM 1.MENINGITIS 2.BILIARY INFECTIONS 3.SEPTICEMIA 4.INFECTIONS IN IMMUNOCOMPROMISED PATIENTS 5.URINARY TRACT &GENITAL TRACT INFECTIONS 6.SURGICAL PROPHYLAXIS 7.SKIN & SOFT TISSUE INFECTIONS 8.BONE & JOINT INFECTIONS 9.GONORRHEA 10.PERITONITIS.