AGGRASTAT 12.5MG/50ML I.V. INFUSION

ABOUT TIROFIBAN NON PEPTIDE GLYCOPROTEIN IIB/IIIA INHIBITOR ANTIPLATELET AGENT. MECHANISM OF ACTION OF TIROFIBAN TIROFIBAN IS AN ANTIPLATELET DRUG. IT IS GLYCOPROTEIN IIB / IIIA INHIBITORS. IT IS A REVERSIBLE ANTAGONIST OF FIBRINOGEN BINDING TO THE GLYCOPROTEIN IIB / IIIA RECEPTOR THE MAJOR PLATELET SURFACE RECEPTOR INVOLVED IN PLATELET AGGREGATION. TIROFIBAN WORKS BY PREVENTING PLATELETS AGGREGATION. STICKING OF PLATELETS EACH OTHER PRODUCES BLOOD CLOTS INDICATIONS FOR TIROFIBAN 1.UNSTABLE ANGINA 2.MYOCARDIAL INFARCTION TYPICAL DOSAGE FOR TIROFIBAN IV ADULT: 0.4 ?G / KG /MINUTE FOR 30 MINUTES. THEN THE RATE IS DECREASED TO 0.1 ?G /KG /MINUTE