COLLYCROM 4% EYE DROPS 10 ML

ABOUT SODIUM CROMOGLYCATE SYNTHETIC CHROMONE DERIVATIVE MAST CELL STABILIZER ANTIALLERGIC ASTHMA PROPHYLACTIC. MECHANISM OF ACTION OF SODIUM CROMOGLYCATE THIS SYNTHETIC CHROMONE DERIVATIVE HAS SEVERAL MECHANISM OF ACTION 1. IT IS A MAST CELL STABILIZER 2. IT INHIBIT CHLORIDE CHANNELS AND INHIBIT THE EXAGGERATED NEURONAL REFLEXES TRIGGERED BY STIMULATION OF IRRITANT RECEPTORS ON SENSORY NERVE ENDINGS (E.G. EXERCISE-INDUCED ASTHMA) AND RELEASE OF PREFORMED CYTOKINES FROM SEVERAL TYPE OF INFLAMMATORY CELLS (T-CELL EOSINOPHIL) IN ALLERGEN-INDUCED ASTHMA.3. IT INHIBIT CALCIUM INFLUX OF THE CELL 4.IT INHIBIT THE ENZYME PHOSPHODIESTERASE 5. IT REDUCE ALPHA-ADRENORECEPTOR DENSITY 6. IT INHIBIT IG-E DEPENDANT SECRETION OF CELLS OTHER THAN MAST CELLS.