DIFLUNAZOLE 25MG/5ML SYRUP 70ML
سعر DIFLUNAZOLE 25MG/5ML SYRUP 70ML
28.80 جنية
الشركة المنتجة لـ DIFLUNAZOLE 25MG/5ML SYRUP 70ML
CID
المادة الفعالة DIFLUNAZOLE 25MG/5ML SYRUP 70ML
FLUCONAZOLE
معلومات عن DIFLUNAZOLE 25MG/5ML SYRUP 70ML
About Fluconazole
A triazole derivative A board range Antifungal.
Mechanism of Action of Fluconazole
Fluconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis
Interactions for Fluconazole
Cimetidine: Decreased efficacy of fluconazole.
Cyclosporine: Increase in serum cyclosporine plasma concentration.
Hydrochlorothiazide: Reduction in renal clearance of fluconazole.
Phenytoin: Efficacy of phenytoin enhanced.
Rifampicin: Efficacy of fluconazole decreased higher dosage required.
Sulfonylureas: Efficacy of tolbutamide glyburide and glipizide increased.
Warfarin: Potentiates the anticoagulant effect resulting in increase in prothrombin time.
Indications for Fluconazole
1.Oesophageal candidiasis
2.Oropharyngeal candidiasis
3.Vaginal candidiasis
4.Systemic candidiasis
5.Cryptoc