DURICEF 1 GM 8 F.C. TABS

ABOUT CEFADROXIL FIRST GENERATION CEPHALOSPORIN PARA-HYDROXY DERIVATIVE OF CEFALEXIN ORAL BROAD-SPECTRUM ANTIBIOTIC MECHANISM OF ACTION CEFADROXIL IS A 1ST GENERATION CEPHALOSPORIN WHICH EXERTS ITS BACTERICIDAL ACTION AGAINST BOTH GRAM POSITIVE & GRAM NEGATIVE ORGANISMS BY INHIBITING BACTERIAL CELL WALL SYNTHESIS. CEFADROXIL INHIBITS TRANSPEPTIDASE & THUS PREVENTS CROSS LINKING OF BACTERIAL CELL WALL. TRANSPEPTIDASE & ASSOCIATED PROTEINS CONSTITUTE VARIOUS TYPES OF SPECIFIC BINDING PROTEINS WHICH HAVE AFFINITY FOR CEPHALOSPORINS LIKE CEFADROXIL INDICATIONS FOR CEFADROXIL 1. URINAY TRACT INFECTIONS 2. TONSILLITIS & PHARYNGITIS 3. SKIN &SOFT TISSUE INFECTIONS 4. OTITIS MEDIA. CONTRA-INDICATIONS OF CEFADROXIL 1.HYPERSENSITIVITY TO CEPHALOSPORINS 2.PORPHYRIA 3.NEUROMUSCULAR DISORDERS.