ALLERGICASONE 125/50 MCG NASAL SPRAY 140 ACTUATIONS

DESCRIPTION: AZELASTINE A PHTHALAZINE DERIVATIVE IS AN ANTIHISTAMINE AND MAST CELL STABILIZER AVAILABLE AS A NASAL SPRAY FOR HAY FEVER AND AS EYE DROPS FOR ALLERGIC CONJUNCTIVITIS. INDICATION : FOR THE SYMPTOMATIC TREATMENT OF SEASONAL ALLERGIC RHINITIS AND NON-ALLERGIC RHINITIS AS WELL AS SYMPTOMATIC RELIEF OF OCULAR ITCHING ASSOCIATED WITH ALLERGIC CONJUNCTIVITIS. MECHANISM OF ACTION: AZELASTINE COMPETES WITH HISTAMINE FOR THE H1-RECEPTOR SITES ON EFFECTOR CELLS AND ACTS AS AN ANTAGONIST BY INHIBITING THE RELEASE OF HISTAMINE AND OTHER MEDIATORS INVOLVED IN THE ALLERGIC RESPONSE.