ETAPHYLLINE 500 MG 10 SUPP

What is Acefylline Piperazine? Acefylline is a theophylline derivative which is used as a bronchodilator similarly to theophylline. It relaxes smooth muscles relieves bronchospasm & has a stimulant effect on respiration. It stimulates the myocardium & central nervous system decreases peripheral resistance & venous pressure & causes diuresis. The mechanism of action is still not clear inhibition of phosphodiesterase with a resulting increase in intracellular cyclic AMP does occur but not apparently at concentrations normally used for clinical effect. Other proposed mechanisms of action include adenosine receptor antagonism prostaglandin antagonism & effects on intracellular calcium. Sodium phenobarbital is a non-selective central nervous system depressant that is primarily used as sedative-hypnotic.