GENTAMICIN SULPHATE 40MG/ML AMP.USP 23

سعر GENTAMICIN SULPHATE 40MG/ML AMP.USP 23
4.25 جنية
الشركة المنتجة لـ GENTAMICIN SULPHATE 40MG/ML AMP.USP 23
SEDICO
المادة الفعالة GENTAMICIN SULPHATE 40MG/ML AMP.USP 23
GENTAMICIN
معلومات عن GENTAMICIN SULPHATE 40MG/ML AMP.USP 23
About Gentamicin
Aminoglycoside antibiotic.
Mechanism of Action of Gentamicin
Gentamicin exerts its bactericidal action against gram negative organisms & some of gram positive organisms by inhibiting bacterial protein synthesis. The process involves 1. Penetration of bacterial cell membrane & binding directly to the bacterial ribosome 2. Misleading of m-RNA codon by bacterial ribosome 3. Formation of peptide chains with wrong amino acid sequence which gets incorporated into bacterial cell membrane and alters its permeability 4. Bacterial cell lysis. Some bacterial strains resistant to other amino glycosides are sensitive to Gentamicin.
Indications for Gentamicin
1. Infections caused by staphylococci pseudomonas proteous klebsiella enterobacter & serratia.
2. Meningitis.
3. Endocarditis
4. Urinary Tract Infections.
5. Otitis & Ocular infections.
6. Infections of burns & Skin ulcers
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