GYNO PREMAZOLE 6.5% VAGINAL OINT.+APPLICATOR
سعر GYNO PREMAZOLE 6.5% VAGINAL OINT.+APPLICATOR
6.00 جنية
الشركة المنتجة لـ GYNO PREMAZOLE 6.5% VAGINAL OINT.+APPLICATOR
ZAD
المادة الفعالة GYNO PREMAZOLE 6.5% VAGINAL OINT.+APPLICATOR
TIOCONAZOLE
معلومات عن GYNO PREMAZOLE 6.5% VAGINAL OINT.+APPLICATOR
Indication
For the local treatment of vulvovaginal candidiasis (moniliasis).
Mechanism of action Tioconazole interacts with 14-a demethylase a cytochrome P-450 enzyme that converts lanosterol to ergosterol an essential component of the yeast membrane. In this way tioconazole inhibits ergosterol synthesis resulting in increased cellular permeability. Tioconazole may also inhibit endogenous respiration interact with membrane phospholipids inhibit the transformation of yeasts to mycelial forms and the uptake of purine impair triglyceride and/or phospholipid biosynthesis and inhibit the movement of calcium and potassium ions across the cell membrane by blocking the ion transport pathway known as the Gardos channel.