HERPAGO 12 CAPSULES

Properties and actions: Herpago has anti-inflammatory mild analgesic and anti-exudative effects. Herpago reduces swelling relieves pain and improves mobility of the joints. Herpago; iridoid glycosides and harpagoside contents are cyclooxygenase (COX) inhibitors mainly COX2 and to lesser extent COX1 reducing synthesis of the prostaglandins that play a major role in the causation of inflammation and pain. Herpago reduces the synthesis of TNF alpha and the release of cartilage metabolism regulating cytokine interleukin-6 thus inhibits the acute phase reaction and production of pyrogens. The cytokines interleukin-1 and leuko-treine B4 are not affected. Unlike NSAIDs Herpago does not cause gastritis it has a choleretic effect resulting in increased production of bile and thereby it increases the yield of bicarbonate in the duodenum and neutralizes excessive acidity. Indications: Low back pain and sciatica Inflammatory and degenerative forms of rheumatic pain.