AMOTENOLOL 50MG 10 F.C.TAB

DESCRIPTION : A CARDIOSELECTIVE BETA-ADRENERGIC BLOCKER POSSESSING PROPERTIES AND POTENCY SIMILAR TO PROPRANOLOL BUT WITHOUT A NEGATIVE INOTROPIC EFFECT. DOSE: ADULT: PO- ANGINA PECTORIS; HTN- 50-100 MG ONCE DAILY. MIGRAINE PROPHYLAXIS 50-100 MG/DAY. INDICATION : FOR THE MANAGEMENT OF HYPERTENTION AND LONG-TERM MANAGEMENT OF PATIENTS WITH ANGINA PECTORIS MECHANISM OF ACTION: LIKE METOPROLOL ATENOLOL COMPETES WITH SYMPATHOMIMETIC NEUROTRANSMITTERS SUCH AS CATECHOLAMINES FOR BINDING AT BETA(1)-ADRENERGIC RECEPTORS IN THE HEART AND VASCULAR SMOOTH MUSCLE INHIBITING SYMPATHETIC STIMULATION. THIS RESULTS IN A REDUCTION IN RESTING HEART RATE CARDIAC OUTPUT SYSTOLIC AND DIASTOLIC BLOOD PRESSURE AND REFLEX ORTHOSTATIC HYPOTENSION. HIGHER DOSES OF ATENOLOL ALSO COMPETITIVELY BLOCK BETA(2)-ADRENERGIC RESPONSES IN THE BRONCHIAL AND VASCULAR SMOOTH MUSCLES.