INTEGRILIN 2MG/ML VIAL FOR I.V. INJ. 10 ML

About Eptifibatide Glycoprotein IIb/IIIa Inhibitor Antiplatelet Agent (Platelet Aggregation Inhibitor). Indication For treatment of myocardial infarction and acute coronary syndrome. Pharmacodynamics Eptifibatide is an anti-coagulant that selectively blocks the platelet glycoprotein IIb/IIIa receptor. Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarus barbouri). It belongs to the class of the so called arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Mechanism of action Eptifibatide inhibits platelet aggregation by reversibly binding to the platelet receptor glycoprotein (GP) IIb/IIIa of human platelets thus preventing the binding of fibrinogen von Willebrand factor and other adhesive ligands. Inhibition of platelet aggregation occurs in a dose- and concentration-dependent manner.