ISOFLUORANE 100% INHALATION SOL. (N/A)

Description A stable non-explosive inhalation anesthetic relatively free from significant side effects. Mechanism of action Isoflurane induces a reduction in junctional conductance by decreasing gap junction channel opening times and increasing gap junction channel closing times. Isoflurane also activates calcium dependent ATPase in the sarcoplasmic reticulum by increasing the fluidity of the lipid membrane. Also appears to bind the D subunit of ATP synthase and NADH dehydogenase. Isoflurane also binds to the GABA receptor the large conductance Ca2+ activated potassium channel the glutamate receptor and the glycine receptor.