AMRIFLUCAN 150 MG 2 CAPS

About FluconazoleSA triazole derivative A board range Antifungal.SSMechanism of Action of FluconazoleSFluconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesisSSInteractions for FluconazoleSCimetidine: Decreased efficacy of fluconazole. SCyclosporine: Increase in serum cyclosporine plasma concentration. SHydrochlorothiazide: Reduction in renal clearance of fluconazole. SPhenytoin: Efficacy of phenytoin enhanced. SRifampicin: Efficacy of fluconazole decreased higher dosage required. SSulfonylureas: Efficacy of tolbutamide glyburide and glipizide increased. SWarfarin: Potentiates the anticoagulant effect resulting in increase in prothrombin time. SSIndications for FluconazoleS1.Oesophageal candidiasis S2.Oropharyngeal candidiasis S3.Vaginal candidiasis S4.Systemic candidiasis S5.Cryptoc