KONAKION MM PAEDIATRIC 2MG/0.2ML 5 AMP. I.M./I.V./ORAL

About Vitamin K Fat soluble vitamin Antihemorrhagic. Mechanism of Action of Vitamin K Phytonadione (Vitamin K1) is a synthetic form of vitamin K and is lipid soluble. Vitamin K acts as a cofactor in the synthesis of coagulation proteins; prothrombin factors VII IX and X by liver. Vitamin K dependent changes in the final stage of synthesis of these coagulation proteins is gama-carboxylation of glutamate residues of these zymogen proteins and their descarboxy-forms converted in to active forms; which confers on them the capacity to bind Ca2+ and to get bound to the phospholipid surfaces which are essential properties for participation in the coagulation cascade.