ANARCOL 50 MG 30 F.C.TABS

ABOUT NALTREXONE AN OPIOID RECEPTOR(COMPETITIVE ANTAGONISTS AT ?- AND ?- RECEPTOR) ANTAGONIST IN ALCOHOL DEPENDENCE AND OPIOID DEPENDENCE. MECHANISM OF ACTION OF NALTREXONE NALTREXONE IS A COMPETITIVE OPIOID ANTAGONIST. IT REVERSIBLY AND COMPLETELY BLOCKS ALL THE OPIOID RECEPTORS (MU KAPPA AND DELTA). IT IS AN ORALLY ADMINISTERED LONG ACTING PURE OPIOID ANTAGONIST ALCOHOLISM: OPIOID RECEPTORS ARE THOUGHT TO BE RESPONSIBLE FOR SOME OF THE REINFORCING EFFECTS OF ALCOHOL. INDICATIONS FOR NALTREXONE 1. OPIOID ANTAGONIST 2. ALCOHOLISM INTERACTIONS FOR NALTREXONE DISULFIRAM: THE SAFETY AND EFFICACY OF CONCOMITANT USE OF NALTREXONE AND DISULFIRAM HAS NOT BEEN ESTABLISHED. CONCOMITANT USE OF TWO POTENTIALLY HEPATOTOXIC DRUGS IS ORDINARILY NOT RECOMMENDED. THIORIDAZINE: LETHARGY AND SOMNOLENCE HAVE BEEN REPORTED WHEN NALTREXONE AND THIORIDAZINE HAVE BEEN USED. OTHERS: PATIENTS TAKING NALTREXONE MAY NOT BENEFIT FROM OPIOID CONTAINING MEDICINES LIKE COUGH AND COLD PREPARATIONS