LUDNOVIR 0.5 MG 10 TABS
سعر LUDNOVIR 0.5 MG 10 TABS
274.00 جنية
الشركة المنتجة لـ LUDNOVIR 0.5 MG 10 TABS
MASH PREMIERE
المادة الفعالة LUDNOVIR 0.5 MG 10 TABS
ENTECAVIR
معلومات عن LUDNOVIR 0.5 MG 10 TABS
About Entecavir
Nucleoside analog reverse transcriptase inhibitor oral antiviral drug used in the treatment of hepatitis B infection.
Mechanism of Action of Entecavir
By competing with the natural substrate deoxyguanosine triphosphate entecavir functionally inhibits all three activities of the HBV polymerase (reverse transcriptase rt): (1) base priming (2) reverse transcription of the negative strand from the pregenomic messenger RNA and (3) synthesis of the positive strand of HBV DNA. Upon activation by kinases the drug can be incorporated into the DNA which has the ultimate effect of inhibiting the HBV polymerase activity.
Indications for Entecavir
For the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.