CEFAUSE 1 GM VIAL I.M/I.V

ABOUT CEFOTAXIME THIRD GENERATION CEPHALOSPORIN PARENTERAL ANTIBIOTIC. MECHANISM OF ACTION OF CEFOTAXIME CEFOTAXIME IS A 3RD GENERATION CEPHALOSPORIN WHICH EXERTS ITS BACTERICIDAL ACTION AGAINST BOTH GRAM POSITIVE & AEROBIC GRAM NEGATIVE ORGANISMS BY INHIBITING BACTERIAL CELL WALL SYNTHESIS. CEFOTAXIME INHIBITS TRANSPEPTIDASE & THUS PREVENTS CROSS LINKING OF BACTERIAL CELL WALL. TRANSPEPTIDASE & ASSOCIATED PROTEINS CONSTITUTE VARIOUS TYPES OF SPECIFIC BINDING PROTEINS WHICH HAVE AFFINITY FOR CEPHALOSPORINS LIKE CEFOTAXIMESSINDICATIONS FOR CEFOTAXIMES1.MENINGITIS S2.RESISTANT HOSPITAL ACQUIRED INFECTIONS S3.SEPTICEMIA S4.INFECTIONS IN IMMUNOCOMPROMISED PATIENTS S5.URINARY TRACT &GENITAL TRACT INFECTIONS S6.SURGICAL PROPHYLAXIS S7.SKIN & SOFT TISSUE INFECTIONS S8.BONE & JOINT INFECTIONS S9.GONORRHEA. SSINTERACTIONS FOR CEFOTAXIMESSYNERGY WITH AMINOGLYCOSIDES.