ERASTAPEX 40 MG 30 F.C.TAB

ABOUT OLMESARTAN AN ANGIOTENSIN II RECEPTOR ANTAGONIST IMIDAZOLE DERIVATIVE ANTIHYPERTENSIVE. MECHANISM OF ACTION OF OLMESARTAN OLMESARTAN IS A COMPETITIVE ANTAGONIST OF ANGIOTENSIN-II AT AT-1 RECEPTOR. IT DECREASES PERIPHERAL RESISTANCE AND LOWERS BP IN HYPERTENSIVE INDIVIDUALS. IT BLOCKS ALL OVERT ACTIONS OF ANGIOTENSIN-II SUCH AS: - VASOCONSTRICTION CENTRAL & PERIPHERAL SYMPATHETIC STIMULUS RELEASE OF ALDOSTERONE AND ADRENALINE SALT AND WATER REABSORPTION AND CENTRAL ACTIONS LIKE THIRST VASOPRESSIN RELEASE AND GROWTH PROMOTING ACTIONS ON HEART AND BLOOD VESSELS AND AT LAST PRODUCES LOWERING OF BLOOD PRESSURE. INDICATIONS FOR OLMESARTAN HYPERTENSION TYPICAL DOSAGE FOR OLMESARTAN ADULT: 20MG/DAY AND IF NEEDED DOSE CAN BE INCREASED TO 40MG/DAY